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Structural and mechanistic basis of σ-dependent transcriptional pausing

In σ-dependent transcriptional pausing, the transcription initiation factor σ, translocating with RNA polymerase (RNAP), makes sequence-specific protein–DNA interactions with a promoter-like sequence element in the transcribed region, inducing pausing. It has been proposed that, in σ-dependent pausi...

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Detalles Bibliográficos
Autores principales: Pukhrambam, Chirangini, Molodtsov, Vadim, Kooshkbaghi, Mahdi, Tareen, Ammar, Vu, Hoa, Skalenko, Kyle S., Su, Min, Yin, Zhou, Winkelman, Jared T., Kinney, Justin B., Ebright, Richard H., Nickels, Bryce E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191641/
https://www.ncbi.nlm.nih.gov/pubmed/35653571
http://dx.doi.org/10.1073/pnas.2201301119