Efficacy of rupatadine in reducing the incidence of dengue haemorrhagic fever in patients with acute dengue: A randomised, double blind, placebo-controlled trial

BACKGROUND: Rupatadine was previously shown to reduce endothelial dysfunction in vitro, reduced vascular leak in dengue mouse models and to reduce the extent of pleural effusions and thrombocytopenia in patients with acute dengue. Therefore, we sought to determine the efficacy of rupatadine in reduc...

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Detalles Bibliográficos
Autores principales: Malavige, Gathsaurie Neelika, Jeewandara, Chandima, Wijewickrama, Ananda, Gunasinghe, Dumni, Mahapatuna, Sameera D., Gangani, Chathurika, Vimalachandran, Vimalahan, Jayarathna, Geethal, Perera, Yashoda, Wanigatunga, Chandanie, Dissanayake, Harsha, Prathapan, Shamini, Narangoda, Eranga, Idampitiya, Damayanthi, Gomes, Laksiri, Wickramanayake, Samurdhi, Sahabandu, Pramodth, Ogg, Graham S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191706/
https://www.ncbi.nlm.nih.gov/pubmed/35648794
http://dx.doi.org/10.1371/journal.pntd.0010123

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