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Improved transcriptome assembly using a hybrid of long and short reads with StringTie

Short-read RNA sequencing and long-read RNA sequencing each have their strengths and weaknesses for transcriptome assembly. While short reads are highly accurate, they are rarely able to span multiple exons. Long-read technology can capture full-length transcripts, but its relatively high error rate...

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Detalles Bibliográficos
Autores principales: Shumate, Alaina, Wong, Brandon, Pertea, Geo, Pertea, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191730/
https://www.ncbi.nlm.nih.gov/pubmed/35648784
http://dx.doi.org/10.1371/journal.pcbi.1009730