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Improved transcriptome assembly using a hybrid of long and short reads with StringTie
Short-read RNA sequencing and long-read RNA sequencing each have their strengths and weaknesses for transcriptome assembly. While short reads are highly accurate, they are rarely able to span multiple exons. Long-read technology can capture full-length transcripts, but its relatively high error rate...
Autores principales: | Shumate, Alaina, Wong, Brandon, Pertea, Geo, Pertea, Mihaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191730/ https://www.ncbi.nlm.nih.gov/pubmed/35648784 http://dx.doi.org/10.1371/journal.pcbi.1009730 |
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