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Investigation of maternal and perinatal outcome in a population of Iranian pregnant women infected with COVID-19
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in pregnant women might affect both maternal and neonatal outcomes. Based on the inconsistency between the results of the previous studies and the lack of data about the possible vertical transmission of SARS-CoV-2, we desig...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191880/ https://www.ncbi.nlm.nih.gov/pubmed/35697859 http://dx.doi.org/10.1038/s41598-022-14112-1 |
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author | Saleh Gargari, Soraya Rahmati, Nayyereh Fateh, Reyhaneh Khandani, Ayda Nikfar, Somayeh Ghafouri-Fard, Soudeh |
author_facet | Saleh Gargari, Soraya Rahmati, Nayyereh Fateh, Reyhaneh Khandani, Ayda Nikfar, Somayeh Ghafouri-Fard, Soudeh |
author_sort | Saleh Gargari, Soraya |
collection | PubMed |
description | Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in pregnant women might affect both maternal and neonatal outcomes. Based on the inconsistency between the results of the previous studies and the lack of data about the possible vertical transmission of SARS-CoV-2, we designed the present study to investigate the maternal and perinatal outcomes in 182 Iranian pregnant women infected with COVID-19. Among 40 PCR tests conducted on neonatal throat samples, 11 tests were positive. Among the assessed women, 22 women needed ICU admission and 30 premature labors occurred. There were significant associations between ICU admission and many parameters such as the presence of dyspnea (P < 0.001), COVID-19-related CT scan findings (P = 0.003), need for a ventilator (P < 0.001), and low O(2) saturation (P < 0.001), all of which indicate the critical situation of patients. Notably, the cause of delivery was significantly different in both groups, with labor pain and fetal distress being the most frequent causes of delivery in non-ICU and ICU-admitted patients, respectively. Moreover, delivery route (P = 0.003), frequencies of IUGR (P = 0.042), neonatal death (P = 0.008) and asphyxia (P = 0.016), Apgar score (P = 0.003), and gestational age at delivery (P = 0.009) have been associated with ICU admission. The present investigation exhibits association between the critical situation of pregnant women affected with COVID-19 and some adverse neonatal outcomes. |
format | Online Article Text |
id | pubmed-9191880 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-91918802022-06-15 Investigation of maternal and perinatal outcome in a population of Iranian pregnant women infected with COVID-19 Saleh Gargari, Soraya Rahmati, Nayyereh Fateh, Reyhaneh Khandani, Ayda Nikfar, Somayeh Ghafouri-Fard, Soudeh Sci Rep Article Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in pregnant women might affect both maternal and neonatal outcomes. Based on the inconsistency between the results of the previous studies and the lack of data about the possible vertical transmission of SARS-CoV-2, we designed the present study to investigate the maternal and perinatal outcomes in 182 Iranian pregnant women infected with COVID-19. Among 40 PCR tests conducted on neonatal throat samples, 11 tests were positive. Among the assessed women, 22 women needed ICU admission and 30 premature labors occurred. There were significant associations between ICU admission and many parameters such as the presence of dyspnea (P < 0.001), COVID-19-related CT scan findings (P = 0.003), need for a ventilator (P < 0.001), and low O(2) saturation (P < 0.001), all of which indicate the critical situation of patients. Notably, the cause of delivery was significantly different in both groups, with labor pain and fetal distress being the most frequent causes of delivery in non-ICU and ICU-admitted patients, respectively. Moreover, delivery route (P = 0.003), frequencies of IUGR (P = 0.042), neonatal death (P = 0.008) and asphyxia (P = 0.016), Apgar score (P = 0.003), and gestational age at delivery (P = 0.009) have been associated with ICU admission. The present investigation exhibits association between the critical situation of pregnant women affected with COVID-19 and some adverse neonatal outcomes. Nature Publishing Group UK 2022-06-13 /pmc/articles/PMC9191880/ /pubmed/35697859 http://dx.doi.org/10.1038/s41598-022-14112-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Saleh Gargari, Soraya Rahmati, Nayyereh Fateh, Reyhaneh Khandani, Ayda Nikfar, Somayeh Ghafouri-Fard, Soudeh Investigation of maternal and perinatal outcome in a population of Iranian pregnant women infected with COVID-19 |
title | Investigation of maternal and perinatal outcome in a population of Iranian pregnant women infected with COVID-19 |
title_full | Investigation of maternal and perinatal outcome in a population of Iranian pregnant women infected with COVID-19 |
title_fullStr | Investigation of maternal and perinatal outcome in a population of Iranian pregnant women infected with COVID-19 |
title_full_unstemmed | Investigation of maternal and perinatal outcome in a population of Iranian pregnant women infected with COVID-19 |
title_short | Investigation of maternal and perinatal outcome in a population of Iranian pregnant women infected with COVID-19 |
title_sort | investigation of maternal and perinatal outcome in a population of iranian pregnant women infected with covid-19 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191880/ https://www.ncbi.nlm.nih.gov/pubmed/35697859 http://dx.doi.org/10.1038/s41598-022-14112-1 |
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