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Transcriptional regulation of cyclophilin D by BMP/Smad signaling and its role in osteogenic differentiation

Cyclophilin D (CypD) promotes opening of the mitochondrial permeability transition pore (MPTP) which plays a key role in both cell physiology and pathology. It is, therefore, beneficial for cells to tightly regulate CypD and MPTP but little is known about such regulation. We have reported before tha...

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Detalles Bibliográficos
Autores principales: Sautchuk, Rubens, Kalicharan, Brianna H, Escalera-Rivera, Katherine, Jonason, Jennifer H, Porter, George A, Awad, Hani A, Eliseev, Roman A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191891/
https://www.ncbi.nlm.nih.gov/pubmed/35635445
http://dx.doi.org/10.7554/eLife.75023