Research Progress on G-Quadruplexes in Human Telomeres and Human Telomerase Reverse Transcriptase (hTERT) Promoter

The upregulation telomerase activity is observed in over 85-90% of human cancers and provides an attractive target for cancer therapies. The high guanine content in the telomere DNA sequences and the hTERT promoter can form G-quadruplexes (G4s). Small molecules targeting G4s in telomeres and hTERT p...

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Detalles Bibliográficos
Autores principales: Gu, Wei, Lin, Zihan, Zhao, Shengchao, Wang, Guanzhen, Shen, Ziyi, Liu, Wei, Cai, Yi, Wang, Kaibo, Wan, Chunpeng Craig, Yan, Tingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192192/
https://www.ncbi.nlm.nih.gov/pubmed/35707279
http://dx.doi.org/10.1155/2022/2905663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192192/
https://www.ncbi.nlm.nih.gov/pubmed/35707279
http://dx.doi.org/10.1155/2022/2905663

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