Determination and Imaging of Small Biomolecules and Ions Using Ruthenium(II) Complex-Based Chemosensors

Luminescence chemosensors are one of the most useful tools for the determination and imaging of small biomolecules and ions in situ in real time. Based on the unique photo-physical/-chemical properties of ruthenium(II) (Ru(II)) complexes, the development of Ru(II) complex-based chemosensors has attr...

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Autores principales: Wu, Miaomiao, Zhang, Zexi, Yong, Jiaxi, Schenk, Peer M., Tian, Dihua, Xu, Zhi Ping, Zhang, Run
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192387/
https://www.ncbi.nlm.nih.gov/pubmed/35695976
http://dx.doi.org/10.1007/s41061-022-00392-8
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author Wu, Miaomiao
Zhang, Zexi
Yong, Jiaxi
Schenk, Peer M.
Tian, Dihua
Xu, Zhi Ping
Zhang, Run
author_facet Wu, Miaomiao
Zhang, Zexi
Yong, Jiaxi
Schenk, Peer M.
Tian, Dihua
Xu, Zhi Ping
Zhang, Run
author_sort Wu, Miaomiao
collection PubMed
description Luminescence chemosensors are one of the most useful tools for the determination and imaging of small biomolecules and ions in situ in real time. Based on the unique photo-physical/-chemical properties of ruthenium(II) (Ru(II)) complexes, the development of Ru(II) complex-based chemosensors has attracted increasing attention in recent years, and thus many Ru(II) complexes have been designed and synthesized for the detection of ions and small biomolecules in biological and environmental samples. In this work, we summarize the research advances in the development of Ru(II) complex-based chemosensors for the determination of ions and small biomolecules, including anions, metal ions, reactive biomolecules and amino acids, with a particular focus on binding/reaction-based chemosensors for the investigation of intracellular analytes’ evolution through luminescence analysis and imaging. The advances, challenges and future research directions in the development of Ru(II) complex-based chemosensors are also discussed.
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spelling pubmed-91923872022-06-15 Determination and Imaging of Small Biomolecules and Ions Using Ruthenium(II) Complex-Based Chemosensors Wu, Miaomiao Zhang, Zexi Yong, Jiaxi Schenk, Peer M. Tian, Dihua Xu, Zhi Ping Zhang, Run Top Curr Chem (Cham) Review Luminescence chemosensors are one of the most useful tools for the determination and imaging of small biomolecules and ions in situ in real time. Based on the unique photo-physical/-chemical properties of ruthenium(II) (Ru(II)) complexes, the development of Ru(II) complex-based chemosensors has attracted increasing attention in recent years, and thus many Ru(II) complexes have been designed and synthesized for the detection of ions and small biomolecules in biological and environmental samples. In this work, we summarize the research advances in the development of Ru(II) complex-based chemosensors for the determination of ions and small biomolecules, including anions, metal ions, reactive biomolecules and amino acids, with a particular focus on binding/reaction-based chemosensors for the investigation of intracellular analytes’ evolution through luminescence analysis and imaging. The advances, challenges and future research directions in the development of Ru(II) complex-based chemosensors are also discussed. Springer International Publishing 2022-06-13 2022 /pmc/articles/PMC9192387/ /pubmed/35695976 http://dx.doi.org/10.1007/s41061-022-00392-8 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Wu, Miaomiao
Zhang, Zexi
Yong, Jiaxi
Schenk, Peer M.
Tian, Dihua
Xu, Zhi Ping
Zhang, Run
Determination and Imaging of Small Biomolecules and Ions Using Ruthenium(II) Complex-Based Chemosensors
title Determination and Imaging of Small Biomolecules and Ions Using Ruthenium(II) Complex-Based Chemosensors
title_full Determination and Imaging of Small Biomolecules and Ions Using Ruthenium(II) Complex-Based Chemosensors
title_fullStr Determination and Imaging of Small Biomolecules and Ions Using Ruthenium(II) Complex-Based Chemosensors
title_full_unstemmed Determination and Imaging of Small Biomolecules and Ions Using Ruthenium(II) Complex-Based Chemosensors
title_short Determination and Imaging of Small Biomolecules and Ions Using Ruthenium(II) Complex-Based Chemosensors
title_sort determination and imaging of small biomolecules and ions using ruthenium(ii) complex-based chemosensors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192387/
https://www.ncbi.nlm.nih.gov/pubmed/35695976
http://dx.doi.org/10.1007/s41061-022-00392-8
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