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Two adjacent phosphorylation sites in the C-terminus of the channel’s α-subunit have opposing effects on epithelial sodium channel (ENaC) activity

How phosphorylation of the epithelial sodium channel (ENaC) contributes to its regulation is incompletely understood. Previously, we demonstrated that in outside-out patches ENaC activation by serum- and glucocorticoid-inducible kinase isoform 1 (SGK1) was abolished by mutating a serine residue in a...

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Detalles Bibliográficos
Autores principales:	Diakov, Alexei, Nesterov, Viatcheslav, Dahlmann, Anke, Korbmacher, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192390/ https://www.ncbi.nlm.nih.gov/pubmed/35525869 http://dx.doi.org/10.1007/s00424-022-02693-9

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