Cargando…
Pleiotropic activation of endothelial function by angiotensin II receptor blockers is crucial to their protective anti-vascular remodeling effects
There are no therapeutics that directly enhance chronic endothelial nitric oxide (NO) release, which is typically associated with vascular homeostasis. In contrast, angiotensin II (AngII) receptor type 1 (AT1R) blockers (ARBs) can attenuate AngII-mediated oxidative stress, which often leads to incre...
Autores principales: | Tehrani, Arash Y., White, Zoe, Tung, Lin Wei, Zhao, Roy Ru Yi, Milad, Nadia, Seidman, Michael A., Sauge, Elodie, Theret, Marine, Rossi, Fabio M. V., Esfandiarei, Mitra, van Breemen, Casey, Bernatchez, Pascal |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192586/ https://www.ncbi.nlm.nih.gov/pubmed/35697767 http://dx.doi.org/10.1038/s41598-022-13772-3 |
Ejemplares similares
-
Blood pressure‐independent inhibition of Marfan aortic root widening by the angiotensin II receptor blocker valsartan
por: Tehrani, Arash Y., et al.
Publicado: (2021) -
Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin‐deficient and mdx mice
por: White, Zoe, et al.
Publicado: (2021) -
Characterization of doxycycline-mediated inhibition of Marfan syndrome-associated aortic dilation by multiphoton microscopy
por: Tehrani, Arash Y., et al.
Publicado: (2020) -
Angiotensin II receptor blocker losartan exacerbates muscle damage and exhibits weak blood pressure-lowering activity in a dysferlin-null model of Limb-Girdle muscular dystrophy type 2B
por: White, Zoe, et al.
Publicado: (2019) -
Waves of Calcium Depletion in the Sarcoplasmic Reticulum of Vascular Smooth Muscle Cells: An Inside View of Spatiotemporal Ca(2+) Regulation
por: Esfandiarei, Mitra, et al.
Publicado: (2013)