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Hsp90 induces Acsl4-dependent glioma ferroptosis via dephosphorylating Ser637 at Drp1

Ferroptosis is a newly identified form of regulated cell death (RCD) characterized by the iron-dependent lipid reactive oxygen species (ROS) accumulation, but its mechanism in gliomas remains elusive. Acyl–coenzyme A (CoA) synthetase long-chain family member 4 (Acsl4), a pivotal enzyme in the regula...

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Detalles Bibliográficos
Autores principales:	Miao, Zong, Tian, Wei, Ye, Yangfan, Gu, Wei, Bao, Zhongyuan, Xu, Lei, Sun, Guangchi, Li, Chong, Tu, Yiming, Chao, Honglu, Lam, Sin Man, Liu, Ning, Ji, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192632/ https://www.ncbi.nlm.nih.gov/pubmed/35697672 http://dx.doi.org/10.1038/s41419-022-04997-1

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