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Association of FXI activity with thrombo-inflammation, extracellular matrix, lipid metabolism and apoptosis in venous thrombosis

Animal experiments and early phase human trials suggest that inhibition of factor XIa (FXIa) safely prevents venous thromboembolism (VTE), and specific murine models of sepsis have shown potential efficacy in alleviating cytokine storm. These latter findings support the role of FXI beyond coagulatio...

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Detalles Bibliográficos
Autores principales:	Pallares Robles, Alejandro, ten Cate, Vincent, Schulz, Andreas, Prochaska, Jürgen H., Rapp, Steffen, Koeck, Thomas, Panova-Noeva, Marina, Heitmeier, Stefan, Schwers, Stephan, Leineweber, Kirsten, Seyfarth, Hans-Jürgen, Opitz, Christian F., Spronk, Henri, Espinola-Klein, Christine, Lackner, Karl J., Münzel, Thomas, Andrade-Navarro, Miguel A., Konstantinides, Stavros V., ten Cate, Hugo, Wild, Philipp S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192691/ https://www.ncbi.nlm.nih.gov/pubmed/35697739 http://dx.doi.org/10.1038/s41598-022-13174-5

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