RING finger 138 deregulation distorts NF-кB signaling and facilities colitis switch to aggressive malignancy

Prolonged activation of nuclear factor (NF)-кB signaling significantly contributes to the development of colorectal cancer (CRC). New therapeutic opportunities are emerging from targeting this distorted cell signaling transduction. Here, we discovered the critical role of RING finger 138 (RNF138) in...

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Detalles Bibliográficos
Autores principales: Lu, Yalan, Huang, Rong, Ying, Jianming, Li, Xingchen, Jiao, Tao, Guo, Lei, Zhou, Haitao, Wang, Han, Tuersuntuoheti, Amannisa, Liu, Jianmei, Chen, Qichen, Wang, Yanhong, Su, Luying, Guo, Changyuan, Xu, Fu, Wang, Ziyi, Lu, Yan, Li, Kai, Liang, Junbo, Huang, Zhen, Chen, Xiao, Yao, Jinjie, Hu, Hanjie, Cheng, Xiaowen, Wan, Yufeng, Chen, Xinyan, Zhang, Ning, Miao, Shiying, Cai, Jianqiang, Wang, Linfang, Liu, Changzheng, Song, Wei, Zhao, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192753/
https://www.ncbi.nlm.nih.gov/pubmed/35697692
http://dx.doi.org/10.1038/s41392-022-00985-1

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