Cargando…

Role of CD47 in tumor immunity: a potential target for combination therapy

CD47 performs a vital function in cancer therapy by binding to different SIRPα, thrombospondin 1, and integrin. However, its role in tumor immunity and its correlation with prognosis among many cancer types remain unknown. The raw mRNA expression data of CD47 in cancer patients was downloaded from T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Jing, Liu, Fangkun, Li, Chenglong, Liang, Xisong, Li, Chuntao, Liu, Yuanyuan, Yi, Zhenjie, Zhang, Liyang, Fu, Siqi, Zeng, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192775/ https://www.ncbi.nlm.nih.gov/pubmed/35697717 http://dx.doi.org/10.1038/s41598-022-13764-3

Ejemplares similares

Applications of organoid technology to brain tumors
por: Wen, Jie, et al.
Publicado: (2023)

Is CD47 an innate immune checkpoint for tumor evasion?
por: Liu, Xiaojuan, et al.
Publicado: (2017)

CD161, a promising Immune Checkpoint, correlates with Patient Prognosis: A Pan-cancer Analysis
por: Ye, Wenrui, et al.
Publicado: (2021)

Large-scale analysis reveals the specific clinical and immune features of CD155 in glioma
por: Liu, Fangkun, et al.
Publicado: (2019)

CD96, a new immune checkpoint, correlates with immune profile and clinical outcome of glioma
por: Liu, Fangkun, et al.
Publicado: (2020)

Role of CD68 in tumor immunity and prognosis prediction in pan-cancer
por: Zhang, Jingwei, et al.
Publicado: (2022)

Vaccination with CD47 deficient tumor cells elicits an antitumor immune response in mice
por: Li, Yang, et al.
Publicado: (2020)

Checkpoint CD47 Function On Tumor Metastasis And Immune Therapy
por: Lian, Shu, et al.
Publicado: (2019)

Construction of Exosomes that Overexpress CD47 and Evaluation of Their Immune Escape
por: Ben, Xin-Yu, et al.
Publicado: (2022)

Development and Characterization of Nanobody-Derived CD47 Theranostic Pairs in Solid Tumors
por: Zhang, You, et al.
Publicado: (2023)

Significance of CD47 and Its Association With Tumor Immune Microenvironment Heterogeneity in Ovarian Cancer
por: Yu, Lan, et al.
Publicado: (2021)

RAGA prevents tumor immune evasion of LUAD by promoting CD47 lysosome degradation
por: Zhang, Lian, et al.
Publicado: (2023)

CMTM Family Genes Affect Prognosis and Modulate Immunocytes Infiltration in Grade II/III Glioma Patients by Influencing the Tumor Immune Landscape and Activating Associated Immunosuppressing Pathways
por: Wang, Zeyu, et al.
Publicado: (2022)

Therapeutic Targeting of the Macrophage Immune Checkpoint CD47 in Myeloid Malignancies
por: Chao, Mark P., et al.
Publicado: (2020)

Combining ablative radiotherapy and anti CD47 monoclonal antibody improves infiltration of immune cells in tumor microenvironments
por: Rostami, Elham, et al.
Publicado: (2022)

EGFR‐Induced and c‐Src‐Mediated CD47 Phosphorylation Inhibits TRIM21‐Dependent Polyubiquitylation and Degradation of CD47 to Promote Tumor Immune Evasion
por: Du, Linyong, et al.
Publicado: (2023)

miR-128 Regulates Tumor Cell CD47 Expression and Promotes Anti-tumor Immunity in Pancreatic Cancer
por: Xi, Qing, et al.
Publicado: (2020)

CD47 Blockade Triggers T cell-mediated Destruction of Immunogenic Tumors
por: Liu, Xiaojuan, et al.
Publicado: (2015)

Functions of RNF Family in the Tumor Microenvironment and Drugs Prediction in Grade II/III Gliomas
por: Zhang, Jingwei, et al.
Publicado: (2022)

Evaluation of CD47 in the Suppressive Tumor Microenvironment and Immunotherapy in Prostate Cancer
por: Wang, Qianqian, et al.
Publicado: (2023)

The SIRPα–CD47 immune checkpoint in NK cells
por: Deuse, Tobias, et al.
Publicado: (2021)

Anti-CD47 antibody eliminates bone tumors in rats
por: Fang, Shiqiang, et al.
Publicado: (2019)

Tumor-Directed Blockade of CD47 with Bispecific Antibodies Induces Adaptive Antitumor Immunity
por: Dheilly, Elie, et al.
Publicado: (2018)

Transcriptomic Profiles of CD47 in Breast Tumors Predict Outcome and Are Associated with Immune Activation
por: Noblejas-López, María del Mar, et al.
Publicado: (2021)

In Situ Tumor Vaccine Expressing Anti-CD47 Antibody Enhances Antitumor Immunity
por: Zhang, Bin, et al.
Publicado: (2022)

Insights into CD47/SIRPα axis-targeting tumor immunotherapy
por: Zhang, Xuyao, et al.
Publicado: (2018)

Targeting CD47 for cancer immunotherapy
por: Jiang, Zhongxing, et al.
Publicado: (2021)

Prospects of antibodies targeting CD47 or CD24 in the treatment of glioblastoma
por: Wu, Hao, et al.
Publicado: (2021)

Efficacy of metformin therapy in patients with cancer: a meta-analysis of 22 randomised controlled trials
por: Wen, Jie, et al.
Publicado: (2022)

Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity
por: Jeanne, Albin, et al.
Publicado: (2021)

Natural killer cell-related gene signature predicts malignancy of glioma and the survival of patients
por: Li, Chenglong, et al.
Publicado: (2022)

Cancer cells under immune attack acquire CD47-mediated adaptive immune resistance independent of the myeloid CD47-SIRPα axis
por: Hendriks, Mark A.J.M., et al.
Publicado: (2021)

Effect of cabazitaxel on macrophages improves CD47-targeted immunotherapy for triple-negative breast cancer
por: Cao, Xu, et al.
Publicado: (2021)

“UPRegulation” of CD47 by the endoplasmic reticulum stress pathway controls anti-tumor immune responses
por: Cook, Katherine L., et al.
Publicado: (2017)

Advances in Anti-Tumor Treatments Targeting the CD47/SIRPα Axis
por: Zhang, Wenting, et al.
Publicado: (2020)

Blocking CD47 Shows Superior Anti-tumor Therapeutic Effects of Bevacizumab in Gastric Cancer
por: Shi, Chenyang, et al.
Publicado: (2022)

Role of CD47 in Hematological Malignancies
por: Eladl, Entsar, et al.
Publicado: (2020)

CD47/SIRPα pathway mediates cancer immune escape and immunotherapy
por: Jia, Xiao, et al.
Publicado: (2021)

Combined prognostic value of the cancer stem cell markers CD47 and CD133 in esophageal squamous cell carcinoma
por: Wang, Jian‐Hua, et al.
Publicado: (2019)

Screening for distress in patients with primary brain tumor using distress thermometer: a systematic review and meta-analysis
por: Liu, Fangkun, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_llkl087c5kmqiv29n68c7gooab