A new mouse model of radiation-induced liver disease reveals mitochondrial dysfunction as an underlying fibrotic stimulus

BACKGROUND & AIMS: High-dose irradiation is an essential tool to help control the growth of hepatic tumors, but it can cause radiation-induced liver disease (RILD). This life-threatening complication manifests itself months following radiation therapy and is characterized by fibrosis of the peri...

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Detalles Bibliográficos
Autores principales: Melin, Nicolas, Yarahmadov, Tural, Sanchez-Taltavull, Daniel, Birrer, Fabienne E., Brodie, Tess M., Petit, Benoît, Felser, Andrea, Nuoffer, Jean-Marc, Montani, Matteo, Vozenin, Marie-Catherine, Herrmann, Evelyn, Candinas, Daniel, Aebersold, Daniel M., Stroka, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192810/
https://www.ncbi.nlm.nih.gov/pubmed/35712694
http://dx.doi.org/10.1016/j.jhepr.2022.100508

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