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Synthesis of a 2-nitroimidazole derivative N-(4-[(18)F]fluorobenzyl)-2-(2-nitro-1H-imidazol-1-yl)-acetamide ([(18) F]FBNA) as PET radiotracer for imaging tumor hypoxia

BACKGROUND: Tissue hypoxia is a pathological condition characterized by reducing oxygen supply. Hypoxia is a hallmark of tumor environment and is commonly observed in many solid tumors. Non-invasive imaging techniques like positron emission tomography (PET) are at the forefront of detecting and moni...

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Detalles Bibliográficos
Autores principales: Nario, Arian Pérez, Woodfield, Jenilee, dos Santos, Sofia Nascimento, Bergman, Cody, Wuest, Melinda, Araújo, Yasniel Babí, Lapolli, André Luis, West, Frederick G., Wuest, Frank, Bernardes, Emerson Soares
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192864/
https://www.ncbi.nlm.nih.gov/pubmed/35697954
http://dx.doi.org/10.1186/s41181-022-00165-0