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Immunity-related GTPase IRGM at the intersection of autophagy, inflammation, and tumorigenesis

The human immunity-related GTPase M (IRGM) is a GTP-binding protein that regulates selective autophagy including xenophagy and mitophagy. IRGM impacts autophagy by (1) affecting mitochondrial fusion and fission, (2) promoting the co-assembly of ULK1 and Beclin 1, (3) enhancing Beclin 1 interacting p...

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Detalles Bibliográficos
Autores principales:	Goswami, Apeksha Bharatgiri, Karadarević, Dimitrije, Castaño-Rodríguez, Natalia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192921/ https://www.ncbi.nlm.nih.gov/pubmed/35699756 http://dx.doi.org/10.1007/s00011-022-01595-x

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