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Dietary Methionine Restriction Reverses Liver Cancer Driving Metabotype in GNMT KO Mice
OBJECTIVES: Glycine N-methyltransferase (GNMT) is a major liver enzyme that catalyzes the S-adenosyl-methionine (SAM) dependent synthesis of sarcosine from glycine and regulates the availability of SAM for cellular methylation reactions, as well as for detoxification pathways in liver cells. The who...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9193376/ http://dx.doi.org/10.1093/cdn/nzac052.008 |