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Dietary Methionine Restriction Reverses Liver Cancer Driving Metabotype in GNMT KO Mice

OBJECTIVES: Glycine N-methyltransferase (GNMT) is a major liver enzyme that catalyzes the S-adenosyl-methionine (SAM) dependent synthesis of sarcosine from glycine and regulates the availability of SAM for cellular methylation reactions, as well as for detoxification pathways in liver cells. The who...

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Detalles Bibliográficos
Autores principales:	Hall, Madeline, Krupenko, Natalia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Diet and Cancer
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9193376/ http://dx.doi.org/10.1093/cdn/nzac052.008

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