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The Association of Salivary Serotonin With Mood and Cardio-Autonomic Function: A Preliminary Report
BACKGROUND: Serotonin plays an important role in mood regulation and depression. However, it is not clear whether the levels of serotonin in saliva are related to current mood. AIM: To test the association of salivary serotonin concentrations with mood, as well as cardiovascular and autonomic parame...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9193578/ https://www.ncbi.nlm.nih.gov/pubmed/35711584 http://dx.doi.org/10.3389/fpsyt.2022.788153 |
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author | Karbownik, Michał Seweryn Hicks, Steven Daniel |
author_facet | Karbownik, Michał Seweryn Hicks, Steven Daniel |
author_sort | Karbownik, Michał Seweryn |
collection | PubMed |
description | BACKGROUND: Serotonin plays an important role in mood regulation and depression. However, it is not clear whether the levels of serotonin in saliva are related to current mood. AIM: To test the association of salivary serotonin concentrations with mood, as well as cardiovascular and autonomic parameters. MATERIALS AND METHODS: Saliva samples were obtained from collegiate runners and output parameters were examined before and after physical activity. RESULTS: Salivary serotonin concentration was negatively associated with current mood (β = −0.32, 95%CI −0.62 to −0.02, p = 0.037, analysis adjusted for potential confounders), but insignificantly with measured cardiovascular and autonomic parameters. CONCLUSIONS: Salivary serotonin may reflect current mood. The results are preliminary and require further evaluation. |
format | Online Article Text |
id | pubmed-9193578 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-91935782022-06-15 The Association of Salivary Serotonin With Mood and Cardio-Autonomic Function: A Preliminary Report Karbownik, Michał Seweryn Hicks, Steven Daniel Front Psychiatry Psychiatry BACKGROUND: Serotonin plays an important role in mood regulation and depression. However, it is not clear whether the levels of serotonin in saliva are related to current mood. AIM: To test the association of salivary serotonin concentrations with mood, as well as cardiovascular and autonomic parameters. MATERIALS AND METHODS: Saliva samples were obtained from collegiate runners and output parameters were examined before and after physical activity. RESULTS: Salivary serotonin concentration was negatively associated with current mood (β = −0.32, 95%CI −0.62 to −0.02, p = 0.037, analysis adjusted for potential confounders), but insignificantly with measured cardiovascular and autonomic parameters. CONCLUSIONS: Salivary serotonin may reflect current mood. The results are preliminary and require further evaluation. Frontiers Media S.A. 2022-05-31 /pmc/articles/PMC9193578/ /pubmed/35711584 http://dx.doi.org/10.3389/fpsyt.2022.788153 Text en Copyright © 2022 Karbownik and Hicks. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Psychiatry Karbownik, Michał Seweryn Hicks, Steven Daniel The Association of Salivary Serotonin With Mood and Cardio-Autonomic Function: A Preliminary Report |
title | The Association of Salivary Serotonin With Mood and Cardio-Autonomic Function: A Preliminary Report |
title_full | The Association of Salivary Serotonin With Mood and Cardio-Autonomic Function: A Preliminary Report |
title_fullStr | The Association of Salivary Serotonin With Mood and Cardio-Autonomic Function: A Preliminary Report |
title_full_unstemmed | The Association of Salivary Serotonin With Mood and Cardio-Autonomic Function: A Preliminary Report |
title_short | The Association of Salivary Serotonin With Mood and Cardio-Autonomic Function: A Preliminary Report |
title_sort | association of salivary serotonin with mood and cardio-autonomic function: a preliminary report |
topic | Psychiatry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9193578/ https://www.ncbi.nlm.nih.gov/pubmed/35711584 http://dx.doi.org/10.3389/fpsyt.2022.788153 |
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