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Varied Clinical Ketogenic Diets Elicit Both Shared and Unique Functional and Taxonomic Responses on the Human Gut Microbiome in Refractory Epilepsy

OBJECTIVES: The high fat low carbohydrate ketogenic diet (KD) has been used to treat refractory epilepsy wherein 1 in 3 do not respond to anti-epileptic drugs. KD-induced alterations in the gut microbiome are necessary to mediate anti-seizure effects in mice. However, the efficacy of KDs have been i...

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Detalles Bibliográficos
Autores principales: Özcan, Ezgi, Yu, Kristie, Arino, Mariana, Hsu, Jessie, Dinh, Lyna, Lum, Gregory, Hsiao, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9193706/
http://dx.doi.org/10.1093/cdn/nzac069.029