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MG53 Inhibits Necroptosis Through Ubiquitination-Dependent RIPK1 Degradation for Cardiac Protection Following Ischemia/Reperfusion Injury

RATIONALE: While reactive oxygen species (ROS) has been recognized as one of the main causes of cardiac injury following myocardial infarction, the clinical application of antioxidants has shown limited effects on protecting hearts against ischemia–reperfusion (I/R) injury. Thus, the precise role of...

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Detalles Bibliográficos
Autores principales:	Wang, Qiang, Park, Ki Ho, Geng, Bingchuan, Chen, Peng, Yang, Chunlin, Jiang, Qiwei, Yi, Frank, Tan, Tao, Zhou, Xinyu, Bian, Zehua, Ma, Jianjie, Zhu, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9193967/ https://www.ncbi.nlm.nih.gov/pubmed/35711363 http://dx.doi.org/10.3389/fcvm.2022.868632

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