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Impaired Mitochondrial Folate Metabolism Reduces Mitochondrial Respiration in Mouse Muscle Progenitor Cells

OBJECTIVES: Mitochondrial dysfunction is a central contributor to aging. Mitochondrial DNA mutations increase with aging and are associated with low serum folate. Furthermore, both increased age and low serum folate are suggested to increase skeletal muscle fiber loss and impair muscle function. How...

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Detalles Bibliográficos
Autores principales: Fiddler, Joanna, Field, Martha, Thalacker-Mercer, Anna, Blum, Jamie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194026/
http://dx.doi.org/10.1093/cdn/nzac074.011