Cargando…
Investigating the genetic architecture of eye colour in a Canadian cohort
Eye color is highly variable in populations with European ancestry, ranging from low to high quantities of melanin in the iris. Polymorphisms in the HERC2/OCA2 locus have the largest effect on eye color in these populations, although other genomic regions also influence eye color. We performed genom...
Autores principales: | Lona-Durazo, Frida, Thakur, Rohit, Pairo-Castineira, Erola, Funderburk, Karen, Zhang, Tongwu, Kovacs, Michael A., Choi, Jiyeon, Jackson, Ian J., Brown, Kevin M., Parra, Esteban J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194134/ https://www.ncbi.nlm.nih.gov/pubmed/35712076 http://dx.doi.org/10.1016/j.isci.2022.104485 |
Ejemplares similares
-
A large Canadian cohort provides insights into the genetic architecture of human hair colour
por: Lona-Durazo, Frida, et al.
Publicado: (2021) -
Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability
por: Morgan, Michael D., et al.
Publicado: (2018) -
Fine-mapping of retinal vascular complexity loci identifies Notch regulation as a shared mechanism with myocardial infarction outcomes
por: Villaplana-Velasco, Ana, et al.
Publicado: (2023) -
Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations
por: Lona-Durazo, Frida, et al.
Publicado: (2019) -
Fine-mapping and cell-specific enrichment at corneal resistance factor loci prioritize candidate causal regulatory variants
por: Jiang, Xinyi, et al.
Publicado: (2020)