Tanshinone IIA and Neural Stem Cell Combination Therapy Decreases Gut Inflammation and Maintains Gut Integrity in a Translational Pig Ischemic Stroke Model

OBJECTIVES: Impaired gut homeostasis has been found in stroke, leading to leaky gut syndrome, increased levels of gut, brain, and systemic inflammation that further exacerbating brain damage. Tanshinone IIA (Tan IIA) and induced pluripotent stem cell derived neural stem cells (iNSCs) have been shown...

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Detalles Bibliográficos
Autores principales: Jeon, Julie, Kaiser, Erin, Waters, Elizabeth, Yang, Xueyuan, Lourenco, Jeferson, Scheulin, Kelly, Sneed, Sydney, Shin, Soo, Kinder, Holly, Kumar, Anil, Platt, Simon, Ahn, Jeongyoun, Rothrock Jr., Michael, Callaway, Todd, Xie, Jin, West, Franklin, Park, Hea Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Neuroscience/Nutrition and the Brain
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194273/
http://dx.doi.org/10.1093/cdn/nzac064.014

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