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Lycopene Induces Expression of NAD(P)H Quinone Oxidoreductase and Heme Oxygenase-1 through Activation of Nrf2 in Ethanol/LPS-stimulated Pancreatic Acinar Cells

OBJECTIVES: High alcohol intake is a major risk factor for acute pancreatitis. Alcohol metabolism increases reactive oxygen species (ROS) and lipopolysaccharide (LPS) production, leading to induction of inflammatory cytokines such as IL-6 in pancreatic acinar (AR42J) cells. The nuclear factor erythr...

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Detalles Bibliográficos
Autores principales:	Lee, Jaeeun, Lim, Joo Weon, Kim, Hyeyoung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Nutritional Immunology and Inflammation/Immunometabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194396/ http://dx.doi.org/10.1093/cdn/nzac068.017

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