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Proteasome dysfunction disrupts adipogenesis and induces inflammation via ATF3

OBJECTIVE: Regulation of proteasomal activity is an essential component of cellular proteostasis and function. This is evident in patients with mutations in proteasome subunits and associated regulators, who suffer from proteasome-associated autoinflammatory syndromes (PRAAS). These patients display...

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Detalles Bibliográficos
Autores principales: Willemsen, Nienke, Arigoni, Isabel, Studencka-Turski, Maja, Krüger, Elke, Bartelt, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194453/
https://www.ncbi.nlm.nih.gov/pubmed/35636710
http://dx.doi.org/10.1016/j.molmet.2022.101518