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Proteasome dysfunction disrupts adipogenesis and induces inflammation via ATF3
OBJECTIVE: Regulation of proteasomal activity is an essential component of cellular proteostasis and function. This is evident in patients with mutations in proteasome subunits and associated regulators, who suffer from proteasome-associated autoinflammatory syndromes (PRAAS). These patients display...
Autores principales: | Willemsen, Nienke, Arigoni, Isabel, Studencka-Turski, Maja, Krüger, Elke, Bartelt, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194453/ https://www.ncbi.nlm.nih.gov/pubmed/35636710 http://dx.doi.org/10.1016/j.molmet.2022.101518 |
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