A Common Variant at the 3'untranslated Region of the CCL7 Gene (rs17735770) Is Associated With Decreased Susceptibility to Coronary Heart Disease

Monocytes participate in the development of atherosclerosis through the action of cytokines and other inflammatory mediators. Among them, CCR2 and its ligands, CCL2 and CCL7 play an important role, so the main objective of this work was to determine whether genetic variants affecting their activity...

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Detalles Bibliográficos
Autores principales: Medina-Gil, José María, Pérez-García, Ana, Saavedra-Santana, Pedro, Díaz-Carrasco, Asunción, Martínez-Quintana, Efrén, Rodríguez-González, Fayna, Ramírez, Cristina M., Riaño, Marta, Garay-Sánchez, Paloma, Tugores, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194478/
https://www.ncbi.nlm.nih.gov/pubmed/35711383
http://dx.doi.org/10.3389/fcvm.2022.908070

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