Molecular signature of postmortem lung tissue from COVID-19 patients suggests distinct trajectories driving mortality

To elucidate the molecular mechanisms that manifest lung abnormalities during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, we performed whole-transcriptome sequencing of lung autopsies from 31 patients with severe COVID-19 and ten uninfected controls. Using metatranscript...

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Detalles Bibliográficos
Autores principales: Budhraja, Anshul, Basu, Anubhav, Gheware, Atish, Abhilash, Dasari, Rajagopala, Seesandra, Pakala, Suman, Sumit, Madhuresh, Ray, Animesh, Subramaniam, Arulselvi, Mathur, Purva, Nambirajan, Aruna, Kumar, Sachin, Gupta, Ritu, Wig, Naveet, Trikha, Anjan, Guleria, Randeep, Sarkar, Chitra, Gupta, Ishaan, Jain, Deepali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194484/
https://www.ncbi.nlm.nih.gov/pubmed/35438176
http://dx.doi.org/10.1242/dmm.049572

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