Cargando…

Overcoming Resistance to Checkpoint Inhibitors: Natural Killer Cells in Non-Small Cell Lung Cancer

Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatments over the last 10 years, with even increasing indications in many neoplasms. Non-small cell lung cancer (NSCLC) is considered highly immunogenic, and ICIs have found a wide set of applications in this area, in both early and ad...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gemelli, Maria, Noonan, Douglas M., Carlini, Valentina, Pelosi, Giuseppe, Barberis, Massimo, Ricotta, Riccardo, Albini, Adriana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194506/ https://www.ncbi.nlm.nih.gov/pubmed/35712510 http://dx.doi.org/10.3389/fonc.2022.886440

Ejemplares similares

TIMP1 and TIMP2 Downregulate TGFβ Induced Decidual-like Phenotype in Natural Killer Cells
por: Albini, Adriana, et al.
Publicado: (2021)

Overcoming Resistance to Natural Killer Cell Based Immunotherapies for Solid Tumors
por: Nayyar, Gaurav, et al.
Publicado: (2019)

Overcoming the challenges in translational development of natural killer cell therapeutics: An opinion paper
por: Qin, Hong, et al.
Publicado: (2022)

Myeloid Derived Suppressor Cells Interactions With Natural Killer Cells and Pro-angiogenic Activities: Roles in Tumor Progression
por: Bruno, Antonino, et al.
Publicado: (2019)

A Think Tank of TINK/TANKs: Tumor-Infiltrating/Tumor-Associated Natural Killer Cells in Tumor Progression and Angiogenesis
por: Bruno, Antonino, et al.
Publicado: (2014)

An Olive Oil Mill Wastewater Extract Improves Chemotherapeutic Activity Against Breast Cancer Cells While Protecting From Cardiotoxicity
por: Benedetto, Nadia, et al.
Publicado: (2022)

Overcoming the cardiac toxicities of cancer therapy immune checkpoint inhibitors
por: Irabor, Omoruyi Credit, et al.
Publicado: (2022)

Overcoming Resistance to Immune Checkpoint Inhibitors in Head and Neck Squamous Cell Carcinomas
por: dos Santos, Lucas V., et al.
Publicado: (2021)

Orchestration of Angiogenesis by Immune Cells
por: Bruno, Antonino, et al.
Publicado: (2014)

Two Novel Ceramide-Like Molecules and miR-5100 Levels as Biomarkers Improve Prediction of Prostate Cancer in Gray-Zone PSA
por: Mello-Grand, Maurizia, et al.
Publicado: (2021)

The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions
por: Carlini, Valentina, et al.
Publicado: (2023)

In vitro Natural Killer Cell Immunotherapy for Medulloblastoma
por: Fernández, Lucia, et al.
Publicado: (2013)

The SARS-CoV-2 receptor, ACE-2, is expressed on many different cell types: implications for ACE-inhibitor- and angiotensin II receptor blocker-based antihypertensive therapies—reply
por: Albini, Adriana, et al.
Publicado: (2020)

Overcoming resistance to immune checkpoint inhibitors in hepatocellular carcinoma: Challenges and opportunities
por: Xie, Qingqing, et al.
Publicado: (2022)

Preliminary Evidence for IL-10-Induced ACE2 mRNA Expression in Lung-Derived and Endothelial Cells: Implications for SARS-Cov-2 ARDS Pathogenesis
por: Albini, Adriana, et al.
Publicado: (2021)

Extranodal Natural Killer/T-Cell Lymphoma: An Incidental Finding
por: Althoff, Ashley, et al.
Publicado: (2017)

Non-coding RNAs in Natural Killer/T-Cell Lymphoma
por: Mei, Mei, et al.
Publicado: (2019)

Natural Killer Cells from Malignant Pleural Effusion Are Endowed with a Decidual-Like Proangiogenic Polarization
por: Bosi, Annalisa, et al.
Publicado: (2018)

Current Advances in Immunotherapy for Acute Leukemia: An Overview of Antibody, Chimeric Antigen Receptor, Immune Checkpoint, and Natural Killer
por: Shang, Yufeng, et al.
Publicado: (2019)

Checkpoint Inhibitors and Engineered Cells: New Weapons for Natural Killer Cell Arsenal Against Hematological Malignancies
por: Giuliani, Massimo, et al.
Publicado: (2020)

Epstein-Barr Virus-Positive Natural Killer/T-Cell Lymphoma
por: Cai, Qingqing, et al.
Publicado: (2019)

Contribution of natural killer cells in innate immunity against colorectal cancer
por: Ghazvinian, Zeinab, et al.
Publicado: (2023)

Co-targeting triple-negative breast cancer cells and endothelial cells by metronomic chemotherapy inhibits cell regrowth and migration via downregulation of the FAK/VEGFR2/VEGF axis and autophagy/apoptosis activation
por: Scagliotti, Arianna, et al.
Publicado: (2022)

Oncogenic Network and Hub Genes for Natural Killer/T-Cell Lymphoma Utilizing WGCNA
por: Liu, Huijiao, et al.
Publicado: (2020)

Autophagy-Mediated Exosomes as Immunomodulators of Natural Killer Cells in Pancreatic Cancer Microenvironment
por: Papademetrio, Daniela L., et al.
Publicado: (2021)

Integrated driver mutations profile of chinese gastrointestinal-natural killer/T-cell lymphoma
por: Li, Shanshan, et al.
Publicado: (2022)

Aspirin Inhibits Natural Killer/T-Cell Lymphoma by Modulation of VEGF Expression and Mitochondrial Function
por: Zhang, Hongyu, et al.
Publicado: (2019)

In-depth circulating tumor DNA sequencing for prognostication and monitoring in natural killer/T-cell lymphomas
por: Kim, Jin Ju, et al.
Publicado: (2023)

Endometrial Cancer Immune Escape Mechanisms: Let Us Learn From the Fetal–Maternal Interface
por: Bruno, Valentina, et al.
Publicado: (2020)

Acute Myeloid Leukemia Epigenetic Immune Escape From Nature Killer Cells by ICAM-1
por: Xiao, Yang, et al.
Publicado: (2021)

Tim-3 Blockade Elicits Potent Anti-Multiple Myeloma Immunity of Natural Killer Cells
por: Jiang, Wen, et al.
Publicado: (2022)

Prognostic significance of the systemic immune-inflammation index in patients with extranodal natural killer/T-cell lymphoma
por: Hai, Tao, et al.
Publicado: (2023)

Targeting Checkpoint Receptors and Molecules for Therapeutic Modulation of Natural Killer Cells
por: Kim, Nayoung, et al.
Publicado: (2018)

Inhibitory checkpoints in human natural killer cells: IUPHAR Review 28
por: Mariotti, F.R., et al.
Publicado: (2020)

Sphingomyelin is a prospective metabolic immune checkpoint for natural killer cells
por: Ma, Hongdi, et al.
Publicado: (2023)

Natural killer cells and immune-checkpoint inhibitor therapy: Current knowledge and new challenges
por: Poggi, Alessandro, et al.
Publicado: (2021)

Prognostic Nutritional Index, Another Prognostic Factor for Extranodal Natural Killer/T Cell Lymphoma, Nasal Type
por: Yao, Ningning, et al.
Publicado: (2020)

Expression of PD-L1 on Monocytes Is a Novel Predictor of Prognosis in Natural Killer/T-Cell Lymphoma
por: Zhang, Xue-wen, et al.
Publicado: (2020)

Acetyl-L-Carnitine downregulates invasion (CXCR4/CXCL12, MMP-9) and angiogenesis (VEGF, CXCL8) pathways in prostate cancer cells: rationale for prevention and interception strategies
por: Baci, Denisa, et al.
Publicado: (2019)

Molecular checkpoints controlling natural killer cell activation and their modulation for cancer immunotherapy
por: Kwon, Hyung-Joon, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_fjgs1ou8cjoe05ospmrgoidfcc