Knockdown of LMNB1 Inhibits the Proliferation of Lung Adenocarcinoma Cells by Inducing DNA Damage and Cell Senescence

BACKGROUND: Lung cancer has considerably high mortality and morbidity rate. Lung adenocarcinoma (LUAD) tissues highly express lamin B1 (LMNB1), compared with normal tissues. In this study, we knocked down LMNB1 in LUAD cells A549 and NCI-1299 to explore the effect of its inhibition on the proliferat...

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Detalles Bibliográficos
Autores principales: Li, Jiangbo, Sun, Zhijia, Cui, Yingshu, Qin, Lingmei, Wu, Fengyun, Li, Yufang, Du, Nan, Li, Xiaosong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194513/
https://www.ncbi.nlm.nih.gov/pubmed/35712471
http://dx.doi.org/10.3389/fonc.2022.913740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194513/
https://www.ncbi.nlm.nih.gov/pubmed/35712471
http://dx.doi.org/10.3389/fonc.2022.913740

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