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Interaction of Colchicine-Site Ligands With the Blood Cell-Specific Isotype of β-Tubulin—Notable Affinity for Benzimidazoles

Tubulin, the main component of microtubules, is an α-β heterodimer that contains one of multiple isotypes of each monomer. Although the isotypes of each monomer are very similar, the beta tubulin isotype found in blood cells is significantly divergent in amino acid sequence compared to other beta tu...

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Detalles Bibliográficos
Autores principales:	Montecinos, Felipe, Loew, Maura, Chio, Tak I., Bane, Susan L., Sackett, Dan L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194530/ https://www.ncbi.nlm.nih.gov/pubmed/35712668 http://dx.doi.org/10.3389/fcell.2022.884287

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