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Sphingosine kinase 1 mediates sexual dimorphism in fibrosis in a mouse model of NASH
OBJECTIVE: Men with non-alcoholic fatty liver disease (NAFLD) are more likely to progress to non-alcoholic steatohepatitis (NASH) and liver fibrosis than women. However, the underlying molecular mechanisms of this dimorphism is unclear. We have previously shown that mice with global deletion of SphK...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194589/ https://www.ncbi.nlm.nih.gov/pubmed/35671973 http://dx.doi.org/10.1016/j.molmet.2022.101523 |