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Sphingosine kinase 1 mediates sexual dimorphism in fibrosis in a mouse model of NASH

OBJECTIVE: Men with non-alcoholic fatty liver disease (NAFLD) are more likely to progress to non-alcoholic steatohepatitis (NASH) and liver fibrosis than women. However, the underlying molecular mechanisms of this dimorphism is unclear. We have previously shown that mice with global deletion of SphK...

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Detalles Bibliográficos
Autores principales: Montefusco, David, Jamil, Maryam, Maczis, Melissa A., Schroeder, William, Levi, Moshe, Ranjit, Suman, Allegood, Jeremy, Bandyopadhyay, Dipankar, Retnam, Reuben, Spiegel, Sarah, Cowart, L. Ashley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194589/
https://www.ncbi.nlm.nih.gov/pubmed/35671973
http://dx.doi.org/10.1016/j.molmet.2022.101523

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