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Prominent hyperintense areas in swollen optic pathway: An indicator of congestive glymphatic pathway?

A 34-year-old woman presented with progressive visual impairment for 2 months. Computed tomography and magnetic resonance imaging (MRI) revealed a suprasellar cyst. The patient underwent endoscopic endonasal surgery, which resulted in gross total resection with a diagnosis of craniopharyngioma. Post...

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Autores principales: Kuroda, Kiyotaka, Tsutsumi, Satoshi, Sugiyama, Hiroki, Sugiyama, Natsuki, Ueno, Hideaki, Ishii, Hisato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194763/
https://www.ncbi.nlm.nih.gov/pubmed/35711740
http://dx.doi.org/10.1016/j.radcr.2022.05.052
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author Kuroda, Kiyotaka
Tsutsumi, Satoshi
Sugiyama, Hiroki
Sugiyama, Natsuki
Ueno, Hideaki
Ishii, Hisato
author_facet Kuroda, Kiyotaka
Tsutsumi, Satoshi
Sugiyama, Hiroki
Sugiyama, Natsuki
Ueno, Hideaki
Ishii, Hisato
author_sort Kuroda, Kiyotaka
collection PubMed
description A 34-year-old woman presented with progressive visual impairment for 2 months. Computed tomography and magnetic resonance imaging (MRI) revealed a suprasellar cyst. The patient underwent endoscopic endonasal surgery, which resulted in gross total resection with a diagnosis of craniopharyngioma. Postoperatively, the patient's visual function improved. The constructive interference steady-state (CISS) sequence revealed a remarkable resolution of hyperintense areas in the swollen optic nerve and tract. A 36-year-old woman sustained an abrupt visual loss. She had been diagnosed with cavernous malformations (CMs) in the right frontal lobe and suprasellar region 11 years ago, with an intact optic tract. Cerebral MRI at presentation revealed marked enlargement of the suprasellar CM and swelling of the right optic tract, accompanied by predominant hyperintense areas in the optic pathway. The patient's visual function showed significant improvement with conservative management. The CISS sequence performed 3 months later showed remarkable resolution of hyperintensity in the optic pathway. Prominent hyperintense areas in the optic pathway may indicate congestion of glymphatic flow. Reduction in such areas may be a radiological biomarker reflecting the improvement of visual impairment.
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spelling pubmed-91947632022-06-15 Prominent hyperintense areas in swollen optic pathway: An indicator of congestive glymphatic pathway? Kuroda, Kiyotaka Tsutsumi, Satoshi Sugiyama, Hiroki Sugiyama, Natsuki Ueno, Hideaki Ishii, Hisato Radiol Case Rep Case Report A 34-year-old woman presented with progressive visual impairment for 2 months. Computed tomography and magnetic resonance imaging (MRI) revealed a suprasellar cyst. The patient underwent endoscopic endonasal surgery, which resulted in gross total resection with a diagnosis of craniopharyngioma. Postoperatively, the patient's visual function improved. The constructive interference steady-state (CISS) sequence revealed a remarkable resolution of hyperintense areas in the swollen optic nerve and tract. A 36-year-old woman sustained an abrupt visual loss. She had been diagnosed with cavernous malformations (CMs) in the right frontal lobe and suprasellar region 11 years ago, with an intact optic tract. Cerebral MRI at presentation revealed marked enlargement of the suprasellar CM and swelling of the right optic tract, accompanied by predominant hyperintense areas in the optic pathway. The patient's visual function showed significant improvement with conservative management. The CISS sequence performed 3 months later showed remarkable resolution of hyperintensity in the optic pathway. Prominent hyperintense areas in the optic pathway may indicate congestion of glymphatic flow. Reduction in such areas may be a radiological biomarker reflecting the improvement of visual impairment. Elsevier 2022-06-11 /pmc/articles/PMC9194763/ /pubmed/35711740 http://dx.doi.org/10.1016/j.radcr.2022.05.052 Text en © 2022 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Kuroda, Kiyotaka
Tsutsumi, Satoshi
Sugiyama, Hiroki
Sugiyama, Natsuki
Ueno, Hideaki
Ishii, Hisato
Prominent hyperintense areas in swollen optic pathway: An indicator of congestive glymphatic pathway?
title Prominent hyperintense areas in swollen optic pathway: An indicator of congestive glymphatic pathway?
title_full Prominent hyperintense areas in swollen optic pathway: An indicator of congestive glymphatic pathway?
title_fullStr Prominent hyperintense areas in swollen optic pathway: An indicator of congestive glymphatic pathway?
title_full_unstemmed Prominent hyperintense areas in swollen optic pathway: An indicator of congestive glymphatic pathway?
title_short Prominent hyperintense areas in swollen optic pathway: An indicator of congestive glymphatic pathway?
title_sort prominent hyperintense areas in swollen optic pathway: an indicator of congestive glymphatic pathway?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194763/
https://www.ncbi.nlm.nih.gov/pubmed/35711740
http://dx.doi.org/10.1016/j.radcr.2022.05.052
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