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A novel small-molecule selective activator of homomeric GIRK4 channels

G protein–sensitive inwardly rectifying potassium (GIRK) channels are important pharmaceutical targets for neuronal, cardiac, and endocrine diseases. Although a number of GIRK channel modulators have been discovered in recent years, most lack selectivity. GIRK channels function as either homomeric (...

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Detalles Bibliográficos
Autores principales:	Cui, Meng, Xu, Keman, Gada, Kirin D., Shalomov, Boris, Ban, Michelle, Eptaminitaki, Giasemi C., Kawano, Takeharu, Plant, Leigh D., Dascal, Nathan, Logothetis, Diomedes E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194863/ https://www.ncbi.nlm.nih.gov/pubmed/35525275 http://dx.doi.org/10.1016/j.jbc.2022.102009

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