Appraisal of novel azomethine–thioxoimidazolidinone conjugates as ecto-5′-nucleotidase inhibitors: synthesis and molecular docking studies

Purinergic signaling is regulated by a group of extracellular enzymes called ectonucleotidases. One of its members i.e., ecto-5′-nucleotidase (h-e5′NT) is involved in the final step of the enzymatic hydrolysis cascade that is the conversion of adenosine monophosphate (AMP) to adenosine and therefore...

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Detalles Bibliográficos
Autores principales: Channar, Pervaiz Ali, Bano, Sehrish, Hassan, Sidra, Perveen, Fouzia, Saeed, Aamer, Mahesar, Parvez Ali, Khan, Imtiaz Ali, Iqbal, Jamshed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194930/
https://www.ncbi.nlm.nih.gov/pubmed/35765454
http://dx.doi.org/10.1039/d2ra02675a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194930/
https://www.ncbi.nlm.nih.gov/pubmed/35765454
http://dx.doi.org/10.1039/d2ra02675a

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