Cargando…

Characterizing magnetically focused contamination electrons by off‐axis irradiation on an inline MRI‐Linac

PURPOSE: The aim of this study is to investigate off‐axis irradiation on the Australian MRI‐Linac using experiments and Monte Carlo simulations. Simulations are used to verify experimental measurements and to determine the minimum offset distance required to separate electron contamination from the...

Descripción completa

Detalles Bibliográficos
Autores principales: Patterson, Elizabeth, Oborn, Bradley M., Cutajar, Dean, Jelen, Urszula, Liney, Gary, Rosenfeld, Anatoly B., Metcalfe, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195023/
https://www.ncbi.nlm.nih.gov/pubmed/35333000
http://dx.doi.org/10.1002/acm2.13591
_version_ 1784726875663237120
author Patterson, Elizabeth
Oborn, Bradley M.
Cutajar, Dean
Jelen, Urszula
Liney, Gary
Rosenfeld, Anatoly B.
Metcalfe, Peter E.
author_facet Patterson, Elizabeth
Oborn, Bradley M.
Cutajar, Dean
Jelen, Urszula
Liney, Gary
Rosenfeld, Anatoly B.
Metcalfe, Peter E.
author_sort Patterson, Elizabeth
collection PubMed
description PURPOSE: The aim of this study is to investigate off‐axis irradiation on the Australian MRI‐Linac using experiments and Monte Carlo simulations. Simulations are used to verify experimental measurements and to determine the minimum offset distance required to separate electron contamination from the photon field. METHODS: Dosimetric measurements were performed using a microDiamond detector, Gafchromic(®) EBT3 film, and MOSkin (TM). Three field sizes were investigated including 1.9 × 1.9, 5.8 × 5.8, and 9.7 × 9.6 cm(2). Each field was offset a maximum distance, approximately 10 cm, from the central magnetic axis (isocenter). Percentage depth doses (PDDs) were collected at a source‐to‐surface distance (SSD) of 1.8 m for fields collimated centrally and off‐axis. PDD measurements were also acquired at isocenter for each off‐axis field to measure electron contamination. Monte Carlo simulations were used to verify experimental measurements, determine the minimum field offset distance, and demonstrate the use of a spoiler to absorb electron contamination. RESULTS: Off‐axis irradiation separates the majority of electron contamination from an x‐ray beam and was found to significantly reduce in‐field surface dose. For the 1.9 × 1.9, 5.8 × 5.8, and 9.7 × 9.6 cm(2) field, surface dose was reduced from 120.9% to 24.9%, 229.7% to 39.2%, and 355.3% to 47.3%, respectively. Monte Carlo simulations generally were within experimental error to MOSkin (TM) and microDiamond, and used to determine the minimum offset distance, 2.1 cm, from the field edge to isocenter. A water spoiler 2 cm thick was shown to reduce electron contamination dose to near zero. CONCLUSIONS: Experimental and simulation data were acquired for a range of field sizes to investigate off‐axis irradiation on an inline MRI‐Linac. The skin sparing effect was observed with off‐axis irradiation, a feature that cannot be achieved to the same extent with other methods, such as bolusing, for beams at isocenter.
format Online
Article
Text
id pubmed-9195023
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-91950232022-06-21 Characterizing magnetically focused contamination electrons by off‐axis irradiation on an inline MRI‐Linac Patterson, Elizabeth Oborn, Bradley M. Cutajar, Dean Jelen, Urszula Liney, Gary Rosenfeld, Anatoly B. Metcalfe, Peter E. J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: The aim of this study is to investigate off‐axis irradiation on the Australian MRI‐Linac using experiments and Monte Carlo simulations. Simulations are used to verify experimental measurements and to determine the minimum offset distance required to separate electron contamination from the photon field. METHODS: Dosimetric measurements were performed using a microDiamond detector, Gafchromic(®) EBT3 film, and MOSkin (TM). Three field sizes were investigated including 1.9 × 1.9, 5.8 × 5.8, and 9.7 × 9.6 cm(2). Each field was offset a maximum distance, approximately 10 cm, from the central magnetic axis (isocenter). Percentage depth doses (PDDs) were collected at a source‐to‐surface distance (SSD) of 1.8 m for fields collimated centrally and off‐axis. PDD measurements were also acquired at isocenter for each off‐axis field to measure electron contamination. Monte Carlo simulations were used to verify experimental measurements, determine the minimum field offset distance, and demonstrate the use of a spoiler to absorb electron contamination. RESULTS: Off‐axis irradiation separates the majority of electron contamination from an x‐ray beam and was found to significantly reduce in‐field surface dose. For the 1.9 × 1.9, 5.8 × 5.8, and 9.7 × 9.6 cm(2) field, surface dose was reduced from 120.9% to 24.9%, 229.7% to 39.2%, and 355.3% to 47.3%, respectively. Monte Carlo simulations generally were within experimental error to MOSkin (TM) and microDiamond, and used to determine the minimum offset distance, 2.1 cm, from the field edge to isocenter. A water spoiler 2 cm thick was shown to reduce electron contamination dose to near zero. CONCLUSIONS: Experimental and simulation data were acquired for a range of field sizes to investigate off‐axis irradiation on an inline MRI‐Linac. The skin sparing effect was observed with off‐axis irradiation, a feature that cannot be achieved to the same extent with other methods, such as bolusing, for beams at isocenter. John Wiley and Sons Inc. 2022-03-25 /pmc/articles/PMC9195023/ /pubmed/35333000 http://dx.doi.org/10.1002/acm2.13591 Text en © 2022 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Patterson, Elizabeth
Oborn, Bradley M.
Cutajar, Dean
Jelen, Urszula
Liney, Gary
Rosenfeld, Anatoly B.
Metcalfe, Peter E.
Characterizing magnetically focused contamination electrons by off‐axis irradiation on an inline MRI‐Linac
title Characterizing magnetically focused contamination electrons by off‐axis irradiation on an inline MRI‐Linac
title_full Characterizing magnetically focused contamination electrons by off‐axis irradiation on an inline MRI‐Linac
title_fullStr Characterizing magnetically focused contamination electrons by off‐axis irradiation on an inline MRI‐Linac
title_full_unstemmed Characterizing magnetically focused contamination electrons by off‐axis irradiation on an inline MRI‐Linac
title_short Characterizing magnetically focused contamination electrons by off‐axis irradiation on an inline MRI‐Linac
title_sort characterizing magnetically focused contamination electrons by off‐axis irradiation on an inline mri‐linac
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195023/
https://www.ncbi.nlm.nih.gov/pubmed/35333000
http://dx.doi.org/10.1002/acm2.13591
work_keys_str_mv AT pattersonelizabeth characterizingmagneticallyfocusedcontaminationelectronsbyoffaxisirradiationonaninlinemrilinac
AT obornbradleym characterizingmagneticallyfocusedcontaminationelectronsbyoffaxisirradiationonaninlinemrilinac
AT cutajardean characterizingmagneticallyfocusedcontaminationelectronsbyoffaxisirradiationonaninlinemrilinac
AT jelenurszula characterizingmagneticallyfocusedcontaminationelectronsbyoffaxisirradiationonaninlinemrilinac
AT lineygary characterizingmagneticallyfocusedcontaminationelectronsbyoffaxisirradiationonaninlinemrilinac
AT rosenfeldanatolyb characterizingmagneticallyfocusedcontaminationelectronsbyoffaxisirradiationonaninlinemrilinac
AT metcalfepetere characterizingmagneticallyfocusedcontaminationelectronsbyoffaxisirradiationonaninlinemrilinac