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Homogeneity of antibody-drug conjugates critically impacts the therapeutic efficacy in brain tumors

Glioblastoma multiforme (GBM) is the most aggressive and fatal disease of all brain tumor types. Most therapies rarely provide clinically meaningful outcomes in the treatment of GBM. Although antibody-drug conjugates (ADCs) are promising anticancer drugs, no ADCs have been clinically successful for...

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Detalles Bibliográficos
Autores principales: Anami, Yasuaki, Otani, Yoshihiro, Xiong, Wei, Ha, Summer Y.Y., Yamaguchi, Aiko, Rivera-Caraballo, Kimberly A., Zhang, Ningyan, An, Zhiqiang, Kaur, Balveen, Tsuchikama, Kyoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195180/
https://www.ncbi.nlm.nih.gov/pubmed/35613589
http://dx.doi.org/10.1016/j.celrep.2022.110839

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