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CARE 2.0: reducing false-positive sequencing error corrections using machine learning

BACKGROUND: Next-generation sequencing pipelines often perform error correction as a preprocessing step to obtain cleaned input data. State-of-the-art error correction programs are able to reliably detect and correct the majority of sequencing errors. However, they also introduce new errors by makin...

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Detalles Bibliográficos
Autores principales: Kallenborn, Felix, Cascitti, Julian, Schmidt, Bertil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195321/
https://www.ncbi.nlm.nih.gov/pubmed/35698033
http://dx.doi.org/10.1186/s12859-022-04754-3