Identifying Antidepressant Effects of Brain-Derived Neurotrophic Factor and IDO1 in the Mouse Model Based on RNA-Seq Data

Deletion of brain-derived neurotrophic factor (BDNF) and upregulation of indoleamine 2,3-dioxygenase 1 (IDO1) are associated with depression severity in animals. The neurotransmitter hypothesis of depression at the transcriptomic level can be tested using BDNF- and IDO1-knockout mouse models and RNA...

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Detalles Bibliográficos
Autores principales: Ren, Jing, Li, Chenyang, Wei, Songren, He, Yanjun, Huang, Peng, Xu, Jiangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195421/
https://www.ncbi.nlm.nih.gov/pubmed/35711916
http://dx.doi.org/10.3389/fgene.2022.890961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195421/
https://www.ncbi.nlm.nih.gov/pubmed/35711916
http://dx.doi.org/10.3389/fgene.2022.890961

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