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Deletion of both Dectin-1 and Dectin-2 affects the bacterial but not fungal gut microbiota and susceptibility to colitis in mice

BACKGROUND: Innate immunity genes have been reported to affect susceptibility to inflammatory bowel diseases (IBDs) and colitis in mice. Dectin-1, a receptor for fungal cell wall β-glucans, has been clearly implicated in gut microbiota modulation and modification of the susceptibility to gut inflamm...

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Detalles Bibliográficos
Autores principales: Wang, Yazhou, Spatz, Madeleine, Da Costa, Gregory, Michaudel, Chloé, Lapiere, Alexia, Danne, Camille, Agus, Allison, Michel, Marie-Laure, Netea, Mihai G., Langella, Philippe, Sokol, Harry, Richard, Mathias L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195441/
https://www.ncbi.nlm.nih.gov/pubmed/35698210
http://dx.doi.org/10.1186/s40168-022-01273-4