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Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules
OBJECTIVES: To determine how well ultrasound-guidance percutaneous radiofrequency ablation (RFA) and microwave ablation (MWA) performed for benign symptomatic thyroid nodules in terms of clinical and functional outcomes. METHODS: Patients who had a thyroid nodule-linked symptoms acting as dysphagia,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Saudi Medical Journal
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195546/ https://www.ncbi.nlm.nih.gov/pubmed/34344807 http://dx.doi.org/10.15537/smj.2021.42.8.20210307 |
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author | Javadov, Mirkhalig Karatay, Emrah Ugurlu, Mustafa U. |
author_facet | Javadov, Mirkhalig Karatay, Emrah Ugurlu, Mustafa U. |
author_sort | Javadov, Mirkhalig |
collection | PubMed |
description | OBJECTIVES: To determine how well ultrasound-guidance percutaneous radiofrequency ablation (RFA) and microwave ablation (MWA) performed for benign symptomatic thyroid nodules in terms of clinical and functional outcomes. METHODS: Patients who had a thyroid nodule-linked symptoms acting as dysphagia, cosmetic issues, pain, a foreign body sense, hyperthyroidism secondary to autonomous nodules, or concern of malignancy were involved in the study. The primary was the comparison in symptom scores obtained at 1, 3, and 6 months after RFA and MWA. The volume alterations in nodules and alterations in thyroid gland functions were secondary objectives. RESULTS: This prospective study carried out from November 2014 and January 2017 at the General Surgery Department, Marmara University, Faculty of Medicine, Istanbul, Turkey included a total of 100 nodules (50% MWA, 50% RFA). There were statistically significance in pain scores, dysphagia scores, and foreign body sensation scores at 1, 3, and 6 months after therapy in both ablation groups (p=0.0006, p=00004, p=0.0005). At the same time, there were statistically significant reductions in size and volume of the nodules for RFA and MWA (p=0.0004, p=0.0003). There was no significant difference between the RFA and MWA groups’ cosmetic scoring and volume changes (p=0.68, p=0.43). CONCLUSIONS: Alternative therapies for benign symptomatic thyroid nodules include RFA and MWA. The findings of this research revealed that both approaches are safe and effective. |
format | Online Article Text |
id | pubmed-9195546 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Saudi Medical Journal |
record_format | MEDLINE/PubMed |
spelling | pubmed-91955462022-06-21 Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules Javadov, Mirkhalig Karatay, Emrah Ugurlu, Mustafa U. Saudi Med J Original Article OBJECTIVES: To determine how well ultrasound-guidance percutaneous radiofrequency ablation (RFA) and microwave ablation (MWA) performed for benign symptomatic thyroid nodules in terms of clinical and functional outcomes. METHODS: Patients who had a thyroid nodule-linked symptoms acting as dysphagia, cosmetic issues, pain, a foreign body sense, hyperthyroidism secondary to autonomous nodules, or concern of malignancy were involved in the study. The primary was the comparison in symptom scores obtained at 1, 3, and 6 months after RFA and MWA. The volume alterations in nodules and alterations in thyroid gland functions were secondary objectives. RESULTS: This prospective study carried out from November 2014 and January 2017 at the General Surgery Department, Marmara University, Faculty of Medicine, Istanbul, Turkey included a total of 100 nodules (50% MWA, 50% RFA). There were statistically significance in pain scores, dysphagia scores, and foreign body sensation scores at 1, 3, and 6 months after therapy in both ablation groups (p=0.0006, p=00004, p=0.0005). At the same time, there were statistically significant reductions in size and volume of the nodules for RFA and MWA (p=0.0004, p=0.0003). There was no significant difference between the RFA and MWA groups’ cosmetic scoring and volume changes (p=0.68, p=0.43). CONCLUSIONS: Alternative therapies for benign symptomatic thyroid nodules include RFA and MWA. The findings of this research revealed that both approaches are safe and effective. Saudi Medical Journal 2021-08 /pmc/articles/PMC9195546/ /pubmed/34344807 http://dx.doi.org/10.15537/smj.2021.42.8.20210307 Text en Copyright: © Saudi Medical Journal https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. |
spellingShingle | Original Article Javadov, Mirkhalig Karatay, Emrah Ugurlu, Mustafa U. Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules |
title | Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules |
title_full | Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules |
title_fullStr | Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules |
title_full_unstemmed | Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules |
title_short | Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules |
title_sort | clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195546/ https://www.ncbi.nlm.nih.gov/pubmed/34344807 http://dx.doi.org/10.15537/smj.2021.42.8.20210307 |
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