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Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules

OBJECTIVES: To determine how well ultrasound-guidance percutaneous radiofrequency ablation (RFA) and microwave ablation (MWA) performed for benign symptomatic thyroid nodules in terms of clinical and functional outcomes. METHODS: Patients who had a thyroid nodule-linked symptoms acting as dysphagia,...

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Autores principales: Javadov, Mirkhalig, Karatay, Emrah, Ugurlu, Mustafa U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Saudi Medical Journal 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195546/
https://www.ncbi.nlm.nih.gov/pubmed/34344807
http://dx.doi.org/10.15537/smj.2021.42.8.20210307
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author Javadov, Mirkhalig
Karatay, Emrah
Ugurlu, Mustafa U.
author_facet Javadov, Mirkhalig
Karatay, Emrah
Ugurlu, Mustafa U.
author_sort Javadov, Mirkhalig
collection PubMed
description OBJECTIVES: To determine how well ultrasound-guidance percutaneous radiofrequency ablation (RFA) and microwave ablation (MWA) performed for benign symptomatic thyroid nodules in terms of clinical and functional outcomes. METHODS: Patients who had a thyroid nodule-linked symptoms acting as dysphagia, cosmetic issues, pain, a foreign body sense, hyperthyroidism secondary to autonomous nodules, or concern of malignancy were involved in the study. The primary was the comparison in symptom scores obtained at 1, 3, and 6 months after RFA and MWA. The volume alterations in nodules and alterations in thyroid gland functions were secondary objectives. RESULTS: This prospective study carried out from November 2014 and January 2017 at the General Surgery Department, Marmara University, Faculty of Medicine, Istanbul, Turkey included a total of 100 nodules (50% MWA, 50% RFA). There were statistically significance in pain scores, dysphagia scores, and foreign body sensation scores at 1, 3, and 6 months after therapy in both ablation groups (p=0.0006, p=00004, p=0.0005). At the same time, there were statistically significant reductions in size and volume of the nodules for RFA and MWA (p=0.0004, p=0.0003). There was no significant difference between the RFA and MWA groups’ cosmetic scoring and volume changes (p=0.68, p=0.43). CONCLUSIONS: Alternative therapies for benign symptomatic thyroid nodules include RFA and MWA. The findings of this research revealed that both approaches are safe and effective.
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spelling pubmed-91955462022-06-21 Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules Javadov, Mirkhalig Karatay, Emrah Ugurlu, Mustafa U. Saudi Med J Original Article OBJECTIVES: To determine how well ultrasound-guidance percutaneous radiofrequency ablation (RFA) and microwave ablation (MWA) performed for benign symptomatic thyroid nodules in terms of clinical and functional outcomes. METHODS: Patients who had a thyroid nodule-linked symptoms acting as dysphagia, cosmetic issues, pain, a foreign body sense, hyperthyroidism secondary to autonomous nodules, or concern of malignancy were involved in the study. The primary was the comparison in symptom scores obtained at 1, 3, and 6 months after RFA and MWA. The volume alterations in nodules and alterations in thyroid gland functions were secondary objectives. RESULTS: This prospective study carried out from November 2014 and January 2017 at the General Surgery Department, Marmara University, Faculty of Medicine, Istanbul, Turkey included a total of 100 nodules (50% MWA, 50% RFA). There were statistically significance in pain scores, dysphagia scores, and foreign body sensation scores at 1, 3, and 6 months after therapy in both ablation groups (p=0.0006, p=00004, p=0.0005). At the same time, there were statistically significant reductions in size and volume of the nodules for RFA and MWA (p=0.0004, p=0.0003). There was no significant difference between the RFA and MWA groups’ cosmetic scoring and volume changes (p=0.68, p=0.43). CONCLUSIONS: Alternative therapies for benign symptomatic thyroid nodules include RFA and MWA. The findings of this research revealed that both approaches are safe and effective. Saudi Medical Journal 2021-08 /pmc/articles/PMC9195546/ /pubmed/34344807 http://dx.doi.org/10.15537/smj.2021.42.8.20210307 Text en Copyright: © Saudi Medical Journal https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.
spellingShingle Original Article
Javadov, Mirkhalig
Karatay, Emrah
Ugurlu, Mustafa U.
Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules
title Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules
title_full Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules
title_fullStr Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules
title_full_unstemmed Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules
title_short Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules
title_sort clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195546/
https://www.ncbi.nlm.nih.gov/pubmed/34344807
http://dx.doi.org/10.15537/smj.2021.42.8.20210307
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