Cargando…

Correlation of HBV DNA and Hepatitis B Surface Antigen Levels With Tumor Response, Liver Function and Immunological Indicators in Liver Cancer Patients With HBV Infection Undergoing PD-1 Inhibition Combinational Therapy

BACKGROUND: Thus far, few studies have investigated the safety and efficacy of programmed death-1 (PD-1) immune checkpoint inhibitors (ICIs) and tyrosine kinase inhibitors (TKIs) antibodies in patients with hepatitis B virus (HBV)-related liver cancer. OBJECTIVE: To investigate the effect of combina...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Shida, Yu, Yingying, Wang, Siyu, Tu, Bo, Shen, Yingjuan, Qiu, Qin, Liu, Xiaomeng, Su, Nan, Zuo, Yanmei, Luan, Junqing, Zhang, Ji−Yuan, Shi, Ming, Meng, Fanping, Wang, Fu-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195870/ https://www.ncbi.nlm.nih.gov/pubmed/35711409 http://dx.doi.org/10.3389/fimmu.2022.892618

Ejemplares similares

Increased Circulating Levels of CRP and IL-6 and Decreased Frequencies of T and B Lymphocyte Subsets Are Associated With Immune-Related Adverse Events During Combination Therapy With PD-1 Inhibitors for Liver Cancer
por: Yu, Yingying, et al.
Publicado: (2022)

Immunological alterations after immunotherapy with short lived HBV‐TCR T cells associates with long‐term treatment response in HBV‐HCC
por: Tan, Anthony Tanoto, et al.
Publicado: (2021)

Characterization of HBV integration patterns and timing in liver cancer and HBV-infected livers
por: Furuta, Mayuko, et al.
Publicado: (2018)

Correction: Characterization of HBV integration patterns and timing in liver cancer and HBV-infected livers
por: Furuta, Mayuko, et al.
Publicado: (2018)

Immunotherapy of HBV-related advanced hepatocellular carcinoma with short-term HBV-specific TCR expressed T cells: results of dose escalation, phase I trial
por: Meng, Fanping, et al.
Publicado: (2021)

Effects of antiviral therapy on post-hepatectomy HBV reactivation and liver function in HBV DNA-negative patients with HBV-related hepatocellular carcinoma
por: Gong, Wen-Feng, et al.
Publicado: (2017)

Effects of transarterial chemoembolization combined with antiviral therapy on HBV reactivation and liver function in HBV-related hepatocellular carcinoma patients with HBV-DNA negative
por: Wang, Kai, et al.
Publicado: (2018)

Reestablishment of Active Immunity against HBV Graft Reinfection after Liver Transplantation for HBV-Related End Stage Liver Disease
por: Lu, Shi-Chun, et al.
Publicado: (2014)

HBV X protein-based therapeutic vaccine accelerates viral antigen clearance by mobilizing monocyte infiltration into the liver in HBV carrier mice
por: Horng, Jau-Hau, et al.
Publicado: (2020)

Anti-PD-1 therapy achieves favorable outcomes in HBV-positive non-liver cancer
por: Zhou, Jie, et al.
Publicado: (2023)

Proteomic and transcriptomic studies of HBV-associated liver fibrosis of an AAV-HBV-infected mouse model
por: Kan, Fangming, et al.
Publicado: (2017)

Management of HBV Infection in Liver Transplantation Patients
por: Vierling, John M.
Publicado: (2005)

Liver Cell Transformation in Chronic HBV Infection
por: Benhenda, Shirine, et al.
Publicado: (2009)

Characterization of HBV surface antigen isoforms in the natural history and treatment of HBV infection
por: Rodgers, Mary A., et al.
Publicado: (2023)

Editorial: Recent Advances in HBV and HCV Immunology
por: Dustin, Lynn B., et al.
Publicado: (2015)

New biomarkers of hepatitis B virus (HBV) infection: HBV RNA and HBV core-related antigen, new kids on the block?
por: Lim, Young-Suk
Publicado: (2023)

The Sterile Inflammation in the Exacerbation of HBV-Associated Liver Injury
por: Yang, Qiao, et al.
Publicado: (2015)

HBV-Specific CD8+ T-Cell Tolerance in the Liver
por: Baudi, Ian, et al.
Publicado: (2021)

Evaluation of the HBV liver reservoir with fine needle aspirates
por: Testoni, Barbara, et al.
Publicado: (2023)

Serum Sphingolipids Reflect the Severity of Chronic HBV Infection and Predict the Mortality of HBV-Acute-on-Chronic Liver Failure
por: Qu, Feng, et al.
Publicado: (2014)

Hepatitis B virus (HBV) X gene mutations and their association with liver disease progression in HBV-infected patients
por: Al-Qahtani, Ahmed A., et al.
Publicado: (2017)

The Immunologic Role of Gut Microbiota in Patients with Chronic HBV Infection
por: Yang, Ruilin, et al.
Publicado: (2018)

In situ analysis of hepatitis B virus (HBV) antigen and DNA in HBV-induced hepatocellular carcinoma
por: Zheng, Ye, et al.
Publicado: (2022)

Inhibition of the HCV Core Protein on the Immune Response to HBV Surface Antigen and on HBV Gene Expression and Replication In Vivo
por: Zhu, Wenbo, et al.
Publicado: (2012)

Hepatitis B virus (HBV) codon adapts well to the gene expression profile of liver cancer: an evolutionary explanation for HBV’s oncogenic role
por: Yu, Chunpeng, et al.
Publicado: (2022)

The association of complex liver disorders with HBV genotypes prevalent in Pakistan
por: Baig, Saeeda, et al.
Publicado: (2007)

Prevention of HBV Recurrence after Liver Transplant: A Review
por: Nasir, Myra, et al.
Publicado: (2020)

Is PD-1 blockade a potential therapy for HBV?
por: Féray, Cyrille, et al.
Publicado: (2019)

Dynamic changes of HBV markers and HBV DNA load in infants born to HBsAg(+) mothers: can positivity of HBsAg or HBV DNA at birth be an indicator for HBV infection of infants?
por: Chen, Tianyan, et al.
Publicado: (2013)

Hepatitis B virus (HBV)-specific T-cell responses to recombinant HBV core protein in patients with normal liver function and co-infected with chronic HBV and human immunodeficiency virus 1 (HIV-1)
por: Zhang, Xin, et al.
Publicado: (2013)

Circulating Neutrophil Dysfunction in HBV-Related Acute-on-Chronic Liver Failure
por: Wu, Wei, et al.
Publicado: (2021)

Liver-Targeted Anti-HBV Single-Stranded Oligonucleotides with Locked Nucleic Acid Potently Reduce HBV Gene Expression In Vivo
por: Javanbakht, Hassan, et al.
Publicado: (2018)

Immunologic Characterization of Posthepatitis Cirrhosis Caused by HBV and HCV Infection
por: Li, Wan-Yu, et al.
Publicado: (2010)

Testosterone and Estradiol as Novel Prognostic Indicators for HBV-Related Acute-on-Chronic Liver Failure
por: Sun, Shuning, et al.
Publicado: (2021)

Characterization of the liver immune microenvironment in liver biopsies from patients with chronic HBV infection
por: van Buuren, Nicholas, et al.
Publicado: (2021)

S gene mutations of HBV in children with HBV-associated glomerulonephritis
por: Lu, Hongzhu, et al.
Publicado: (2012)

Serum Zonulin in HBV-Associated Chronic Hepatitis, Liver Cirrhosis, and Hepatocellular Carcinoma
por: Wang, Xin, et al.
Publicado: (2019)

A comprehensive validation of HBV-related acute-on-chronic liver failure models to assist decision-making in targeted therapeutics
por: Shen, Yi, et al.
Publicado: (2016)

Nucleic Acid Sensors Involved in the Recognition of HBV in the Liver–Specific in vivo Transfection Mouse Models—Pattern Recognition Receptors and Sensors for HBV
por: Leong, Chean Ring, et al.
Publicado: (2015)

Hepatitis B Virus (HBV) Genotype Mixtures, Viral Load, and Liver Damage in HBV Patients Co-infected With Human Immunodeficiency Virus
por: Jose-Abrego, Alexis, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_38ie5thqosiad0i9tmcffcdsfu