Cargando…

Akt isoforms differentially provide for chemoresistance in prostate cancer

OBJECTIVE: Early prostate cancer micrometastatic foci undergo a mesenchymal to epithelial reverting transition, not only aiding seeding and colonization, but also rendering the tumor cells generally chemoresistant. We previously found that upregulated E-cadherin in the epithelial micrometastases act...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Bo, Shao, Hanshuang, Jiang, Xia, Wang, Zhou, Wu, Chuanyue (Cary), Whaley, Diana, Wells, Alan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Compuscript 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196054/ https://www.ncbi.nlm.nih.gov/pubmed/34591413 http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0747

Ejemplares similares

Expression of E-cadherin and specific CXCR3 isoforms impact each other in prostate cancer
por: Ma, Bo, et al.
Publicado: (2019)

Axl contributes to efficient migration and invasion of melanoma cells
por: Shao, Hanshuang, et al.
Publicado: (2023)

Binding of alpha-ACTN4 to EGF receptor enables its rapid phosphorylation
por: Shao, Hanshuang, et al.
Publicado: (2021)

Deciphering the molecular mechanism of enhanced tumor activity of the EGFR variant T790M/L858R using melanoma cell lines
por: Shao, Hanshuang, et al.
Publicado: (2023)

The AKT1 isoform plays a dominant role in the survival and chemoresistance of chronic lymphocytic leukaemia cells
por: Hofbauer, Sebastian W., et al.
Publicado: (2015)

Macrophage phenotypic subtypes diametrically regulate epithelial-mesenchymal plasticity in breast cancer cells
por: Yang, Min, et al.
Publicado: (2016)

Differential activation of AKT isoforms by growth factors in human myotubes
por: Roberts, Brandon M., et al.
Publicado: (2023)

Insights into Chemoresistance of Prostate Cancer
por: Zhang, Wei, et al.
Publicado: (2015)

Altered CXCR3 isoform expression regulates prostate cancer cell migration and invasion
por: Wu, Qian, et al.
Publicado: (2012)

Akt isoforms in vascular disease
por: Yu, Haixiang, et al.
Publicado: (2015)

Akt isoforms in the immune system
por: Guerau-de-Arellano, Mireia, et al.
Publicado: (2022)

Expression of CtBP family protein isoforms in breast cancer and their role in chemoresistance
por: Birts, Charles N., et al.
Publicado: (2010)

PHLPP isoforms differentially regulate Akt isoforms and AS160 affecting neuronal insulin signaling and insulin resistance via Scribble
por: Sharma, Medha, et al.
Publicado: (2022)

Acetyl-lupeolic acid inhibits Akt signaling and induces apoptosis in chemoresistant prostate cancer cells in vitro and in vivo
por: Schmidt, Claudia, et al.
Publicado: (2017)

α-Actinin-4 Is Essential for Maintaining the Spreading, Motility and Contractility of Fibroblasts
por: Shao, Hanshuang, et al.
Publicado: (2010)

Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis
por: Lee, Jong-Ho, et al.
Publicado: (2017)

PPARγ isoforms differentially regulate metabolic networks to mediate mouse prostatic epithelial differentiation
por: Strand, D W, et al.
Publicado: (2012)

Osteopontin b and c Splice isoforms in Leukemias and Solid Tumors: Angiogenesis Alongside Chemoresistance
por: Mirzaei, Akram, et al.
Publicado: (2018)

AKT2 is the predominant AKT isoform expressed in human skeletal muscle
por: Matheny, Ronald W., et al.
Publicado: (2018)

Distinct roles of AKT isoforms in regulating β1-integrin activity, migration, and invasion in prostate cancer
por: Virtakoivu, Reetta, et al.
Publicado: (2012)

Isoform-Specific Role of Akt in Oral Squamous Cell Carcinoma
por: Roy, Nand Kishor, et al.
Publicado: (2019)

Focal segmental glomerulosclerosis ACTN4 mutants binding to actin: regulation by phosphomimetic mutations
por: Shao, Hanshuang, et al.
Publicado: (2019)

The Roles of Akt Isoforms in the Regulation of Podosome Formation in Fibroblasts and Extracellular Matrix Invasion
por: Eves, Robert, et al.
Publicado: (2015)

Regulation of MicroRNA-497-Targeting AKT2 Influences Tumor Growth and Chemoresistance to Cisplatin in Lung Cancer
por: Wang, Lin, et al.
Publicado: (2020)

Corrigendum: Regulation of microrna-497-targeting AKT2 influences tumor growth and chemoresistance to cisplatin in lung cancer
por: Wang, Lin, et al.
Publicado: (2022)

Autophagy Pathway Is Required for IL-6 Induced Neuroendocrine Differentiation and Chemoresistance of Prostate Cancer LNCaP Cells
por: Chang, Pei-Ching, et al.
Publicado: (2014)

Crk-like adapter protein is overexpressed in cervical carcinoma, facilitates proliferation, invasion and chemoresistance, and regulates Src and Akt signaling
por: Ji, Hong, et al.
Publicado: (2016)

Eggmanone Effectively Overcomes Prostate Cancer Cell Chemoresistance
por: Xie, Chen, et al.
Publicado: (2021)

SUN-001 Analysis of Isoform Specific Differential Splicing Effects in Prostate Cancer
por: Rana, Manjul, et al.
Publicado: (2019)

Salvigenin Suppresses Hepatocellular Carcinoma Glycolysis and Chemoresistance Through Inactivating the PI3K/AKT/GSK-3β Pathway
por: Shao, Hui, et al.
Publicado: (2023)

Statins attenuate outgrowth of breast cancer metastases
por: Beckwitt, Colin H., et al.
Publicado: (2018)

The Akt1 isoform is an essential mediator of ischaemic preconditioning
por: Kunuthur, Suma P, et al.
Publicado: (2012)

Akt isoform specific effects in ovarian cancer progression
por: Linnerth-Petrik, Nicolle M., et al.
Publicado: (2016)

Covalent‐Allosteric Inhibitors to Achieve Akt Isoform‐Selectivity
por: Quambusch, Lena, et al.
Publicado: (2019)

Akt Isoforms: A Family Affair in Breast Cancer
por: Basu, Alakananda, et al.
Publicado: (2021)

c-Mpl-del, a c-Mpl alternative splicing isoform, promotes AMKL progression and chemoresistance
por: Li, Fei, et al.
Publicado: (2022)

Insulin Receptor Isoforms and Insulin Growth Factor-like Receptors: Implications in Cell Signaling, Carcinogenesis, and Chemoresistance
por: Galal, Mariam Ahmed, et al.
Publicado: (2023)

PTEN regulated PI3K-p110 and AKT isoform plasticity controls metastatic prostate cancer progression
por: Miller, Karina, et al.
Publicado: (2023)

Trefoil factor 3 mediation of oncogenicity and chemoresistance in hepatocellular carcinoma is AKT-BCL-2 dependent
por: You, Ming-Liang, et al.
Publicado: (2017)

Aurora-A Induces Chemoresistance Through Activation of the AKT/mTOR Pathway in Endometrial Cancer
por: Wu, Jun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_35c9sj3ali8vkne9s6ti164375