Super-enhancer receives signals from the extracellular matrix to induce PD-L1-mediated immune evasion via integrin/BRAF/TAK1/ERK/ETV4 signaling

OBJECTIVE: PD-L1 and PD-L2 expression levels determine immune evasion and the therapeutic efficacy of immune checkpoint blockade. The factors that drive inducible PD-L1 expression have been extensively studied, but mechanisms that result in constitutive PD-L1 expression in cancer cells are largely u...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Panpan, Jin, Xinxin, Fan, Zhiwei, Wang, Zhou, Yue, Suhui, Wu, Changyue, Chen, Shiyin, Wu, Yuanyuan, Chen, Miaomiao, Gu, Donghua, Zhang, Siliang, Mao, Renfang, Fan, Yihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196059/
https://www.ncbi.nlm.nih.gov/pubmed/34623791
http://dx.doi.org/10.20892/j.issn.2095-3941.2021.0137

Ejemplares similares

Ejemplares similares