Comprehensive characterization of CRC with germline mutations reveals a distinct somatic mutational landscape and elevated cancer risk in the Chinese population

OBJECTIVE: Hereditary colorectal cancer (CRC) accounts for approximately 5%–10% of all CRC cases. The full profile of CRC-related germline mutations and the corresponding somatic mutational profile have not been fully determined in the Chinese population. METHODS: We performed the first population s...

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Detalles Bibliográficos
Autores principales: Yao, Jianfei, Zhen, Yunhuan, Fan, Jing, Gong, Yuan, Ye, Yumeng, Guo, Shaohua, Liu, Hongyi, Li, Xiaoyun, Li, Guosheng, Yang, Pan, Wang, Xiaohui, Liu, Danni, Huang, Tanxiao, Cao, Huiya, Suo, Peisu, Li, Yuemin, Yu, Jingbo, Song, Lele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196063/
https://www.ncbi.nlm.nih.gov/pubmed/35014770
http://dx.doi.org/10.20892/j.issn.2095-3941.2021.0190

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