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Targeting the COP9 signalosome for cancer therapy

The COP9 signalosome (CSN) is a highly conserved protein complex composed of 8 subunits (CSN1 to CSN8). The individual subunits of the CSN play essential roles in cell proliferation, tumorigenesis, cell cycle regulation, DNA damage repair, angiogenesis, and microenvironmental homeostasis. The CSN co...

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Detalles Bibliográficos
Autores principales:	Du, Wenqi, Zhang, Ruicheng, Muhammad, Bilal, Pei, Dongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Compuscript 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196064/ https://www.ncbi.nlm.nih.gov/pubmed/35315259 http://dx.doi.org/10.20892/j.issn.2095-3941.2021.0605

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