Gene amplification acts as a molecular foothold to facilitate cross-species adaptation and evasion of multiple antiviral pathways

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Cross-species spillover events are responsible for many of the pandemics in human history including COVID-19; however, the evolutionary mechanisms that enable these events are poorly understood. We have previously modeled this process using a chimeric vaccinia virus expressing the rhesus cytomegalov...

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Detalles Bibliográficos
Autores principales: Banerjee, Shefali, Smith, Cathy, Geballe, Adam, Rothenburg, Stefan, Kitzman, Jacob O., Brennan, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196108/
https://www.ncbi.nlm.nih.gov/pubmed/35702158
http://dx.doi.org/10.1101/2022.06.06.494757
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